Incorporation of α2-Plasmin Inhibitor into Fibrin Clots and Its Association with the Clinical Outcome of Acute Ischemic Stroke Patients

Incorporation of α2-Plasmin Inhibitor into Fibrin Clots and Its Association with the Clinical Outcome of Acute Ischemic Stroke Patients

Cross-linking of α2-plasmin inhibitor (α2-PI) to fibrin by activated factor XIII (FXIIIa) is essential for the inhibition of fibrinolysis. Little is known about the factors modifying α2-PI incorporation into the fibrin clot and whether the extent of incorporation has clinical consequences. Herein we...

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Bibliographic Details
Main Authors: Zsuzsa Bagoly, Barbara Baráth, Rita Orbán-Kálmándi, István Szegedi, Réka Bogáti, Ferenc Sarkady, László Csiba, Éva Katona
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Biomolecules
Subjects:
α2-plasmin inhibitor
acute ischemic stroke
factor XIII
fibrin(ogen), fibrinolysis
thrombolysis
Online Access:https://www.mdpi.com/2218-273X/11/3/347

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https://www.mdpi.com/2218-273X/11/3/347

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