Regulation of mitochondrial morphology and cristae architecture by the TLR4 pathway in human skeletal muscle

Regulation of mitochondrial morphology and cristae architecture by the TLR4 pathway in human skeletal muscle

In skeletal muscle (SkM), a reduced mitochondrial elongate phenotype is associated with several metabolic disorders like type 2 diabetes mellitus (T2DM). However, the mechanisms contributing to this reduction in mitochondrial elongate phenotype in SkM have not been fully elucidated. It has recently...

Full description

Bibliographic Details
Main Authors: Mauricio Castro-Sepulveda, Mauro Tuñón-Suárez, Giovanni Rosales-Soto, Ronald Vargas-Foitzick, Louise Deldicque, Hermann Zbinden-Foncea
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
mitochondrial dynamics
skeletal muscle function
mitochondrial nanotunnels
Lipopolysaccharide
TAK242
type 2 diabetes
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1212779/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2023.1212779/full

Similar Items