2′-fucosyllactose alone or combined with resistant starch increases circulating short-chain fatty acids in lean men and men with prediabetes and obesity

BackgroundInfusion of short-chain fatty acids (SCFA) to the distal colon beneficially affects human substrate and energy metabolism. Here, we hypothesized that the combination of 2′-fucosyllactose (2′-FL) with resistant starch (RS) increases distal colonic SCFA production and improves metabolic para...

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Bibliographic Details
Main Authors: Emanuel E. Canfora, Lars M. M. Vliex, Taojun Wang, Arjen Nauta, Freek G. Bouwman, Jens J. Holst, Koen Venema, Erwin G. Zoetendal, Ellen E. Blaak
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Nutrition
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2023.1200645/full