Inhibition of spastin impairs motor function recovery after spinal cord injury

Inhibition of spastin impairs motor function recovery after spinal cord injury

Promoting axonal regeneration is an effective strategy for recovery from traumatic spinal cord injury (SCI). Spastin, a microtubule-severing protein, modulates axonal outgrowth and branch formation by regulating microtubule dynamics. However, the exact role of spastin during recovery from SCI remain...

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Bibliographic Details
Main Authors: Jie Yang, Yunlong Zhang, Zhenbin Cai, Jianyu Zou, Shaojin Li, Guiqiang Miao, Hongsheng Lin, Xiaodong Zhao, Minghui Tan
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Brain Research Bulletin
Subjects:
Spinal cord injury
Spastin
Spastazoline
Microtubule severing
Neurite outgrowth
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923023002319

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http://www.sciencedirect.com/science/article/pii/S0361923023002319

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