Reduced evolvability of <it>Escherichia coli </it>MDS42, an IS-less cellular chassis for molecular and synthetic biology applications

<p>Abstract</p> <p>Background</p> <p>Evolvability is an intrinsic feature of all living cells. However, newly emerging, evolved features can be undesirable when genetic circuits, designed and fabricated by rational, synthetic biological approaches, are installed in the...

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Bibliographic Details
Main Authors: Blattner Frederick R, Pósfai János, Ayaydin Ferhan, Balikó Gabriella, Fehér Tamás, Umenhoffer Kinga, Pósfai György
Format: Article
Language:English
Published: BMC 2010-05-01
Series:Microbial Cell Factories
Online Access:http://www.microbialcellfactories.com/content/9/1/38