HBeAg Levels Vary across the Different Stages of HBV Infection According to the Extent of Immunological Pressure and Are Associated with Therapeutic Outcome in the Setting of Immunosuppression-Driven HBV Reactivation

HBeAg Levels Vary across the Different Stages of HBV Infection According to the Extent of Immunological Pressure and Are Associated with Therapeutic Outcome in the Setting of Immunosuppression-Driven HBV Reactivation

HBeAg is a marker of HBV-activity, and HBeAg-loss predicts a favorable clinical outcome. Here, we characterize HBeAg-levels across different phases of HBV infection, their correlation with virological/biochemical markers and the virological response to anti-HBV therapy. Quantitative HBeAg (qHBeAg, D...

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Bibliographic Details
Main Authors: Lorenzo Piermatteo, Mohammad Alkhatib, Stefano D’Anna, Vincenzo Malagnino, Ada Bertoli, Eleonora Andreassi, Elisa Basile, Alessandra Iuvara, Maria De Cristofaro, Giuseppina Cappiello, Carlotta Cerva, Carmine Minichini, Mariantonietta Pisaturo, Mario Starace, Nicola Coppola, Carla Fontana, Sandro Grelli, Francesca Ceccherini-Silberstein, Massimo Andreoni, Upkar S. Gill, Patrick T. F. Kennedy, Loredana Sarmati, Romina Salpini, Valentina Svicher
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biomedicines
Subjects:
HBV
HBeAg
HBV reactivation
Online Access:https://www.mdpi.com/2227-9059/9/10/1352

Internet

https://www.mdpi.com/2227-9059/9/10/1352

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