Microglial Dysfunction in Neurodegenerative Diseases via RIPK1 and ROS

Microglial dysfunction is a major contributor to the pathogenesis of multiple neurodegenerative diseases. The neurotoxicity of microglia associated with oxidative stress largely depends on NF-κB pathway activation, which promotes the production and release of microglial proinflammatory cytokines and...

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Bibliographic Details
Main Authors: Qiaoyan Wu, Chengyu Zou
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/11/11/2201