Effect of Dornase Alfa on the Lung Clearance Index in Children with Cystic Fibrosis: A Lesson from a Case Series

Effect of Dornase Alfa on the Lung Clearance Index in Children with Cystic Fibrosis: A Lesson from a Case Series

Background: Dornase alfa (DNase) is the only mucus-degrading agent that has proven efficacy in cystic fibrosis (CF). Few studies have evaluated the effects of DNase on the lung clearance index (LCI). We report the experience of two CF centers in which LCI monitoring was used to evaluate the efficacy...

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Bibliographic Details
Main Authors: Vito Terlizzi, Giuseppe Fabio Parisi, Beatrice Ferrari, Chiara Castellani, Sara Manti, Salvatore Leonardi, Giovanni Taccetti
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Children
Subjects:
dornase alfa
DNase
lung clearance index
lung function
children
cystic fibrosis
Online Access:https://www.mdpi.com/2227-9067/9/11/1625

Internet

https://www.mdpi.com/2227-9067/9/11/1625

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