The SarcoEndoplasmic Reticulum Calcium ATPase (SERCA) pump: a potential target for intervention in aging and skeletal muscle pathologies

Abstract As a key regulator of cellular calcium homeostasis, the Sarcoendoplasmic Reticulum Calcium ATPase (SERCA) pump acts to transport calcium ions from the cytosol back to the sarcoplasmic reticulum (SR) following muscle contraction. SERCA function is closely associated with muscle health and fu...

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Bibliographic Details
Main Authors: Hongyang Xu, Holly Van Remmen
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Skeletal Muscle
Subjects:
Online Access:https://doi.org/10.1186/s13395-021-00280-7