Properdin levels in human sepsis

Properdin is a normal serum protein which increases the production of complement activation products by binding to C3b integral to convertase complexes and amplifying their activity at the site of activation. Thereby, it can aid in the resolution of infection but also contribute to tissue damage....

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Bibliographic Details
Main Authors: Cordula M Stover, John eMcDonald, Simon eByrne, David G Lambert, Jonathan eThompson
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00024/full