T Cell Receptor Repertoire Analysis Reveals Signatures of T Cell Responses to Human Mycobacterium tuberculosis

T Cell Receptor Repertoire Analysis Reveals Signatures of T Cell Responses to Human Mycobacterium tuberculosis

Characterization of T cell receptor (TCR) repertoires is essential for understanding the mechanisms of Mycobacterium tuberculosis (Mtb) infection involving T cell adaptive immunity. The characteristics of TCR sequences and distinctive signatures of T cell subsets in tuberculous patients are still un...

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Bibliographic Details
Main Authors: Ming-Ming Shao, Feng-Shuang Yi, Zhong-Yin Huang, Peng Peng, Feng-Yao Wu, Huan-Zhong Shi, Kan Zhai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Microbiology
Subjects:
TCR repertoire
single-cell sequencing
tuberculous patients
polyfunctional CD4+ T cells
TRBV4-1
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.829694/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2022.829694/full

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