Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2

Single-molecule FRET measurements provide detailed insights into the conformational states and dynamics of human Argonaute 2 that are required for its function at the core of the eukaryotic RNA silencing pathway.

Bibliographic Details
Main Authors: Sarah Willkomm, Leonhard Jakob, Kevin Kramm, Veronika Graus, Julia Neumeier, Gunter Meister, Dina Grohmann
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-31480-4