Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2
Single-molecule FRET measurements provide detailed insights into the conformational states and dynamics of human Argonaute 2 that are required for its function at the core of the eukaryotic RNA silencing pathway.
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-31480-4 |
| _version_ | 1811328563267239936 |
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| author | Sarah Willkomm Leonhard Jakob Kevin Kramm Veronika Graus Julia Neumeier Gunter Meister Dina Grohmann |
| author_facet | Sarah Willkomm Leonhard Jakob Kevin Kramm Veronika Graus Julia Neumeier Gunter Meister Dina Grohmann |
| author_sort | Sarah Willkomm |
| collection | DOAJ |
| description | Single-molecule FRET measurements provide detailed insights into the conformational states and dynamics of human Argonaute 2 that are required for its function at the core of the eukaryotic RNA silencing pathway. |
| first_indexed | 2024-04-13T15:27:19Z |
| format | Article |
| id | doaj.art-fc70d6bcbb934f14a1ea17f995f8ffda |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-13T15:27:19Z |
| publishDate | 2022-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-fc70d6bcbb934f14a1ea17f995f8ffda2022-12-22T02:41:28ZengNature PortfolioNature Communications2041-17232022-07-0113111310.1038/s41467-022-31480-4Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2Sarah Willkomm0Leonhard Jakob1Kevin Kramm2Veronika Graus3Julia Neumeier4Gunter Meister5Dina Grohmann6Institute of Microbiology & Archaea Centre, Single-Molecule Biochemistry Lab, University of RegensburgInstitute of Microbiology & Archaea Centre, Single-Molecule Biochemistry Lab, University of RegensburgInstitute of Microbiology & Archaea Centre, Single-Molecule Biochemistry Lab, University of RegensburgLaboratory for RNA Biology, University of RegensburgLaboratory for RNA Biology, University of RegensburgLaboratory for RNA Biology, University of RegensburgInstitute of Microbiology & Archaea Centre, Single-Molecule Biochemistry Lab, University of RegensburgSingle-molecule FRET measurements provide detailed insights into the conformational states and dynamics of human Argonaute 2 that are required for its function at the core of the eukaryotic RNA silencing pathway.https://doi.org/10.1038/s41467-022-31480-4 |
| spellingShingle | Sarah Willkomm Leonhard Jakob Kevin Kramm Veronika Graus Julia Neumeier Gunter Meister Dina Grohmann Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2 Nature Communications |
| title | Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2 |
| title_full | Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2 |
| title_fullStr | Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2 |
| title_full_unstemmed | Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2 |
| title_short | Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2 |
| title_sort | single molecule fret uncovers hidden conformations and dynamics of human argonaute 2 |
| url | https://doi.org/10.1038/s41467-022-31480-4 |
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