Nicotine regulates autophagy of human periodontal ligament cells through α7 nAchR that promotes secretion of inflammatory factors IL-1β and IL-8

Nicotine regulates autophagy of human periodontal ligament cells through α7 nAchR that promotes secretion of inflammatory factors IL-1β and IL-8

Abstract Background Nicotine is an important risk factor and the main toxic component associated with periodontitis. However, the mechanism of nicotine induced periodontitis is not clear. To investigated the mechanism through which nicotine regulates autophagy of human periodontal ligament cells (hP...

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Bibliographic Details
Main Authors: Yang Du, Kuan Yang, Zhifei Zhou, Lizheng Wu, Lulu Wang, Yujiang Chen, Xin Ge, Xiaojing Wang
Format: Article
Language:English
Published: BMC 2021-11-01
Series:BMC Oral Health
Subjects:
Nicotine
Autophagy
α7 nAchR
Periodontitis
Online Access:https://doi.org/10.1186/s12903-021-01894-5

Internet

https://doi.org/10.1186/s12903-021-01894-5

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