Kisspeptin Is Upregulated at the Maternal-Fetal Interface of the Preeclamptic-like BPH/5 Mouse and Normalized after Synchronization of Sex Steroid Hormones

Kisspeptin Is Upregulated at the Maternal-Fetal Interface of the Preeclamptic-like BPH/5 Mouse and Normalized after Synchronization of Sex Steroid Hormones

Insufficient invasion of conceptus-derived trophoblast cells in the maternal decidua is a key event in the development of early-onset preeclampsia (PE), a subtype of PE associated with high maternal and fetal morbidity and mortality. Kisspeptins, a family of peptides previously shown to inhibit trop...

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Bibliographic Details
Main Authors: Viviane C. L. Gomes, Ashley K. Woods, Kassandra R. Crissman, Camille A. Landry, Kalie F. Beckers, Bryce M. Gilbert, Lucas R. Ferro, Chin-Chi Liu, Erin L. Oberhaus, Jenny L. Sones
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Reproductive Medicine
Subjects:
<i>Kiss1/Kiss1r</i>
<i>GPR54</i>
trophoblast
estrogen
progesterone
Online Access:https://www.mdpi.com/2673-3897/3/4/21

Internet

https://www.mdpi.com/2673-3897/3/4/21

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