Cytochrome P450 enzymes mediated by DNA methylation is involved in deoxynivalenol-induced hepatoxicity in piglets

Cytochrome P450 enzymes mediated by DNA methylation is involved in deoxynivalenol-induced hepatoxicity in piglets

Deoxynivalenol (DON) is an inevitable contaminant in animal feed and can lead to liver damage, then decreasing appetite and causing growth retardation in piglets. Although many molecular mechanisms are related to hepatoxicity caused by DON, few studies have been done on cytochrome P450 (CYP450) enzy...

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Bibliographic Details
Main Authors: Aimei Liu, Yaqin Yang, Jingchao Guo, Yan Gao, Qinghua Wu, Ling Zhao, Lv-hui Sun, Xu Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-06-01
Series:Animal Nutrition
Subjects:
Deoxynivalenol
Hepatoxicity
Growth inhibition
CYP450 enzyme
DNA methylation
Piglet
Online Access:http://www.sciencedirect.com/science/article/pii/S2405654522000257

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http://www.sciencedirect.com/science/article/pii/S2405654522000257

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