DNA methylation promotes the expression of PPARγ transcript 1 at least in part by preventing NRF1 binding to the promoter P1 of chicken PPARγ gene

DNA methylation promotes the expression of PPARγ transcript 1 at least in part by preventing NRF1 binding to the promoter P1 of chicken PPARγ gene

ABSTRACT: Peroxisome proliferator-activated receptor gamma (PPARγ) is a master regulator of adipogenesis. Our previous study revealed that chicken PPARγ has 3 alternative promoters named as P1, P2, and P3, and the DNA methylation of promoter P3 was negatively associated with PPARγ mRNA expression in...

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Bibliographic Details
Main Authors: T.T. Cui, J.X. Huang, B.L. Ning, F. Mu, H.Y. Chen, T.Y. Xing, H. Li, N. Wang
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Poultry Science
Subjects:
chicken
PPARγ
promoter methylation
abdominal adipose tissue
NRF1
Online Access:http://www.sciencedirect.com/science/article/pii/S003257912400138X

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http://www.sciencedirect.com/science/article/pii/S003257912400138X

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