Histone Deacetylase (HDAC) Inhibitors for the Treatment of Schistosomiasis

Histone Deacetylase (HDAC) Inhibitors for the Treatment of Schistosomiasis

Schistosomiasis is a major neglected parasitic disease that affects more than 240 million people worldwide and for which the control strategy consists of mass treatment with the only available drug, praziquantel. Schistosomes display morphologically distinct stages during their life cycle and the tr...

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Bibliographic Details
Main Authors: Ehab Ghazy, Mohamed Abdelsalam, Dina Robaa, Raymond J. Pierce, Wolfgang Sippl
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Pharmaceuticals
Subjects:
schistosomiasis
epigenetic
smHDAC8
hydroxamic acids
HDAC inhibitors
sirtuins
Online Access:https://www.mdpi.com/1424-8247/15/1/80

Internet

https://www.mdpi.com/1424-8247/15/1/80

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