Real-time PCR quantification of spliced X-box binding protein 1 (XBP1) using a universal primer method.

Real-time PCR quantification of spliced X-box binding protein 1 (XBP1) using a universal primer method.

X-box binding protein 1 (XBP1) mRNA processing plays a crucial role in the unfolded protein response (UPR), which is activated in response to endoplasmic reticulum (ER) stress. Upon accumulation of the UPR-converted XBP1 mRNA splicing from an unspliced (u) XBP1 (inactive) isoform to the spliced (s)...

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Main Authors: Seung-Bin Yoon, Young-Ho Park, Seon-A Choi, Hae-Jun Yang, Pil-Soo Jeong, Jae-Jin Cha, Sanghoon Lee, Seung Hwan Lee, Jong-Hee Lee, Bo-Woong Sim, Bon-Sang Koo, Sang-Je Park, Youngjeon Lee, Young-Hyun Kim, Jung Joo Hong, Ji-Su Kim, Yeung Bae Jin, Jae-Won Huh, Sang-Rae Lee, Bong-Seok Song, Sun-Uk Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0219978

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https://doi.org/10.1371/journal.pone.0219978

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