Astaxanthine attenuates cisplatin ototoxicity in vitro and protects against cisplatin-induced hearing loss in vivo

Astaxanthine attenuates cisplatin ototoxicity in vitro and protects against cisplatin-induced hearing loss in vivo

Astaxanthine (AST) has important biological activities including antioxidant and anti-inflammatory effects that could alleviate neurological and heart diseases, but its role in the prevention of cisplatin-induced hearing loss (CIHL) is not yet well understood. In our study, a steady interaction betw...

Full description

Bibliographic Details
Main Authors: Benyu Nan, Zirui Zhao, Kanglun Jiang, Xi Gu, Huawei Li, Xinsheng Huang
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Astaxanthine
Cisplatin
Hearing loss
Mitochondrial
Ototoxicity
Reactive oxygen species
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383521002513

Internet

http://www.sciencedirect.com/science/article/pii/S2211383521002513

Similar Items