Pyruvate Kinase M2 Promotes Hair Regeneration by Connecting Metabolic and Wnt/β-Catenin Signaling

Pyruvate Kinase M2 Promotes Hair Regeneration by Connecting Metabolic and Wnt/β-Catenin Signaling

Hair follicle stem cells (HFSCs) utilize glycolytic metabolism during their activation and anagen induction. However, the role of pyruvate kinase M2 (PKM2), which catalyzes the final step of glycolysis, in hair regeneration has not been elucidated. In this study, we investigated the expression patte...

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Bibliographic Details
Main Authors: Yeong Chan Ryu, You-Rin Kim, Jiyeon Park, Sehee Choi, Won-Ji Ryu, Geon-Uk Kim, Eunhwan Kim, Yumi Hwang, Heejene Kim, Gyoonhee Han, Soung-Hoon Lee, Kang-Yell Choi
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceutics
Subjects:
pyruvate kinase M2
metabolism
Wnt/β-catenin signaling pathway
hair follicle stem cell
hair regeneration
Online Access:https://www.mdpi.com/1999-4923/14/12/2774

Internet

https://www.mdpi.com/1999-4923/14/12/2774

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