Childhood adversity correlates with stable changes in DNA methylation trajectories in children and converges with epigenetic signatures of prenatal stress

Childhood adversity correlates with stable changes in DNA methylation trajectories in children and converges with epigenetic signatures of prenatal stress

Childhood maltreatment (CM) is an established major risk factor for a number of negative health outcomes later in life. While epigenetic mechanisms, such as DNA methylation (DNAm), have been proposed as a means of embedding this environmental risk factor, little is known about its timing and traject...

Full description

Bibliographic Details
Main Authors: Jade Martins, Darina Czamara, Susann Sauer, Monika Rex-Haffner, Katja Dittrich, Peggy Dörr, Karin de Punder, Judith Overfeld, Andrea Knop, Felix Dammering, Sonja Entringer, Sibylle M. Winter, Claudia Buss, Christine Heim, Elisabeth B. Binder
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Neurobiology of Stress
Subjects:
Epigenetics
Early-life adversity
Prenatal exposure
Risk factors
Stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289521000448

Internet

http://www.sciencedirect.com/science/article/pii/S2352289521000448

Similar Items