The role of bone marrow-derived cells in the origin of liver cancer revealed by single-cell sequencing

The role of bone marrow-derived cells in the origin of liver cancer revealed by single-cell sequencing

Objective: Epithelial cancers often originate from progenitor cells, while the origin of hepatocellular carcinoma (HCC) is still controversial. HCC, one of the deadliest cancers, is closely linked with liver injuries and chronic inflammation, which trigger massive infiltration of bone marrow-derived...

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Bibliographic Details
Main Authors: Lu Chen, Xianfu Yi, Piao Guo, Hua Guo, Ziye Chen, Chunyu Hou, Lisha Qi, Yongrong Wang, Chengwen Li, Peng Liu, Yucun Liu, Yuanfu Xu, Ning Zhang
Format: Article
Language:English
Published: China Anti-Cancer Association 2020-02-01
Series:Cancer Biology & Medicine
Subjects:
hepatocellular carcinoma
bone marrow-derived cells (bmdcs)
origination
genome sequencing
copy number alteration
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1567

Internet

http://www.cancerbiomed.org/index.php/cocr/article/view/1567

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