Divergence in Morris Water Maze-Based Cognitive Performance under Chronic Stress Is Associated with the Hippocampal Whole Transcriptomic Modification in Mice

Divergence in Morris Water Maze-Based Cognitive Performance under Chronic Stress Is Associated with the Hippocampal Whole Transcriptomic Modification in Mice

Individual susceptibility determines the magnitude of stress effects on cognitive function. The hippocampus, a brain region of memory consolidation, is vulnerable to stressful environments, and the impact of stress on hippocampus may determine individual variability in cognitive performance. Therefo...

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Bibliographic Details
Main Authors: Seung H. Jung, Milene L. Brownlow, Matteo Pellegrini, Ryan Jankord
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Molecular Neuroscience
Subjects:
spatial learning
contextual memory
chronic variable stress
whole transcriptome
upstream regulator analysis
WGCNA (Weighted Gene Co-expression Network Analyses)
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00275/full

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http://journal.frontiersin.org/article/10.3389/fnmol.2017.00275/full

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