Effect of HIV Envelope Vaccination on the Subsequent Antibody Response to HIV Infection

Effect of HIV Envelope Vaccination on the Subsequent Antibody Response to HIV Infection

ABSTRACT Analysis of breakthrough HIV-1 infections could elucidate whether prior vaccination primes relevant immune responses. Here, we measured HIV-specific antibody responses in 14 South African volunteers who acquired HIV infection after participating in phase 1/2 trials of envelope-containing im...

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Bibliographic Details
Main Authors: Zanele Ditse, Nonhlanhla N. Mkhize, Michael Yin, Michael Keefer, David C. Montefiori, Georgia D. Tomaras, Gavin Churchyard, Kenneth H. Mayer, Shelly Karuna, Cecilia Morgan, Linda-Gail Bekker, Koleka Mlisana, Glenda Gray, Zoe Moodie, Peter Gilbert, Penny L. Moore, Carolyn Williamson, Lynn Morris
Format: Article
Language:English
Published: American Society for Microbiology 2020-02-01
Series:mSphere
Subjects:
HIV vaccines
HIV breakthrough infections
HIV-specific binding antibodies
broadly neutralizing antibodies
DNA/MVA vaccines
rAd5
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00738-19

Internet

https://journals.asm.org/doi/10.1128/mSphere.00738-19

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