Antioxidant effect of acetyl--carnitine against cisplatin-induced cardiotoxicity

Objective Cisplatin (CDDP) toxicity is a dose-limiting clinical problem in clinical practice, mainly because of nephrotoxicity or ototoxicity. However, the mechanism of CDDP-induced cardiotoxicity is poorly understood. Acetyl- l -carnitine (ALCAR) is an antioxidant agent with protective effects agai...

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Bibliographic Details
Main Authors: Serdar Bayrak, Safiye Aktaş, Zekiye Altun, Yasemin Çakir, Merve Tütüncü, Selen Kum Özşengezer, Osman Yilmaz, Nur Olgun
Format: Article
Language:English
Published: SAGE Publishing 2020-08-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/0300060520951393