Ultra-sensitive detection of Mycobacterium leprae: DNA extraction and PCR assays.

Ultra-sensitive detection of Mycobacterium leprae: DNA extraction and PCR assays.

Leprosy urgently needs a precise and early diagnostic tool. The sensitivity of the direct (bacilli staining, Mycobacterium leprae DNA) and indirect (antibody levels, T cell assays) diagnostics methods vary based on the clinical form. Recently, PCR-based M. leprae DNA detection has been shown to diff...

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Bibliographic Details
Main Authors: Fernanda Saloum de Neves Manta, Thyago Leal-Calvo, Suelen Justo M Moreira, Brunna L C Marques, Marcelo Ribeiro-Alves, Patrícia S Rosa, José Augusto C Nery, Rita de Cássia Pontello Rampazzo, Alexandre Dias Tavares Costa, Marco Aurelio Krieger, Milton Ozório Moraes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008325

Internet

https://doi.org/10.1371/journal.pntd.0008325

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