Effect of Rapamycin on Exosomes and PD-1/PD-L1 in Human Erythroleukemia HEL Cells

Effect of Rapamycin on Exosomes and PD-1/PD-L1 in Human Erythroleukemia HEL Cells

Objective To determine the effect of rapamycin(Rapa) on JAK2, ABCA3, and the immune checkpoint PD-1/PD-L1 in exosomes derived from JAK2 V617F positive HEL cells. Methods Human erythroleukemia HEL cells (JAK2 V617F mutation-positive) were cultured in vitro, and rapamycin was added at concentrations o...

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Bibliographic Details
Main Authors: QI Lin, ZHANG Zhao, WANG Suyun, LIU Guimin, WANG Rui, FU Jianzhu, CHENG Zhiyong
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2022-10-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
rapamycin
exosomes
hel cells
pd-1/pd-l1
Online Access:http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2022.22.0188

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http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2022.22.0188

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