The Histamine 3 Receptor Is Expressed in the Heart and Its Activation Opposes Adverse Cardiac Remodeling in the Angiotensin II Mouse Model

The Histamine 3 Receptor Is Expressed in the Heart and Its Activation Opposes Adverse Cardiac Remodeling in the Angiotensin II Mouse Model

Histamine is a basic amine stored in mast cells, with its release capable of activating one of four histamine receptors. The histamine 3 receptor (H<sub>3</sub>R) is known to be cardioprotective during acute ischemia by acting to limit norepinephrine release. However, a recent study repo...

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Bibliographic Details
Main Authors: Samuel L. McCaffrey, Grace Lim, Martyn Bullock, Ainsley O. Kasparian, Roderick Clifton-Bligh, William B. Campbell, Alexander Widiapradja, Scott P. Levick
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
mast cell
macrophage
fibroblast
imetit
A331440
histamine receptor agonist
Online Access:https://www.mdpi.com/1422-0067/21/24/9757

Internet

https://www.mdpi.com/1422-0067/21/24/9757

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