PTTG1 Enhances Oncolytic Adenovirus 5 Entry into Pancreatic Adenocarcinoma Cells by Increasing CXADR Expression

Pituitary tumor-transforming gene 1 (PTTG1) is overexpressed in various types of tumors and functions as an oncogene; it could also be a potential target in tumor therapy. Meanwhile, the high mortality of pancreatic adenocarcinoma (PAAD) largely depends on the limited effectiveness of therapy. Based...

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Bibliographic Details
Main Authors: Lu Long, Jian Gao, Ruiyang Zhang
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/15/5/1153