MitoTEMPOL modulates mitophagy and histopathology of Wistar rat liver after streptozotocin injection

MitoTEMPOL modulates mitophagy and histopathology of Wistar rat liver after streptozotocin injection

Objective(s): This study aims to explore the effect of mitoTEMPOL on histopathology, lipid droplet, and mitophagy gene expression of Wistar rat’s liver after injection of streptozotocin (STZ).Materials and Methods: Twenty male Wistar rats were divided into 4 groups: Control (n=5); 100 mg/kg BW/day m...

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Bibliographic Details
Main Authors: Rova Virgana, Julia Gunadi, Nur Atik, Kwee Limdawati, Diana Jasaputra, Roro Wahyudianingsih, Nadya Suardi, Ray Soetadji, Hanna Goenawan, Ronny Lesmana, Arief Kartasasmita
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2022-11-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
anti-oxidants
lipid droplet
mitochondrial dynamics
mitophagy
metabolic zone
oxidative stress
Online Access:https://ijbms.mums.ac.ir/article_21092_451dd7108c835f8b67a09b5a812967ad.pdf

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https://ijbms.mums.ac.ir/article_21092_451dd7108c835f8b67a09b5a812967ad.pdf

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