Prevalence and Impact of Apolipoprotein E7 on LDL Cholesterol Among Patients With Familial Hypercholesterolemia

Prevalence and Impact of Apolipoprotein E7 on LDL Cholesterol Among Patients With Familial Hypercholesterolemia

Background: It has been suggested that a rare mutant apolipoprotein E7, APOE7 (p.Glu262Lys, p.Glu263Lys), has been identified to be associated with hyperlipoproteinemia in the general population. Moreover, its prevalence has been shown to be 0.005–0.06%. However, there are no prior data regarding it...

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Bibliographic Details
Main Authors: Hayato Tada, Kan Yamagami, Nobuko Kojima, Junichi Shibayama, Tetsuo Nishikawa, Hirofumi Okada, Akihiro Nomura, Soichiro Usui, Kenji Sakata, Masayuki Takamura, Masa-aki Kawashiri
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
APOE
familial hypercholesterolemia
PCSK9
LDLR
LDL-C
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.625852/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2021.625852/full

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