The granulosa cell response to luteinizing hormone is partly mediated by YAP1-dependent induction of amphiregulin

The granulosa cell response to luteinizing hormone is partly mediated by YAP1-dependent induction of amphiregulin

Abstract Background The LH surge is a pivotal event that triggers multiple key ovarian processes including oocyte maturation, cumulus expansion, follicular wall rupture and luteinization of mural granulosa and theca cells. Recently, LH-dependent activation of the Hippo signaling pathway has been sho...

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Bibliographic Details
Main Authors: Philippe Godin, Mayra F. Tsoi, Martin Morin, Nicolas Gévry, Derek Boerboom
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Cell Communication and Signaling
Subjects:
Yap1
Hippo pathway
Amphiregulin
Luteinizing hormone
Granulosa cells
Ovulation
Online Access:https://doi.org/10.1186/s12964-022-00843-1

Internet

https://doi.org/10.1186/s12964-022-00843-1

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