Loss of Planar Cell Polarity Effector Fuzzy Causes Renal Hypoplasia by Disrupting Several Signaling Pathways
In vertebrates, the planar cell polarity (PCP) pathway regulates tissue morphogenesis during organogenesis, including the kidney. Mutations in human PCP effector proteins have been associated with severe syndromic ciliopathies. Importantly, renal hypoplasia has been reported in some patients. Howeve...
| Autors principals: | , , , , |
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| Format: | Article |
| Idioma: | English |
| Publicat: |
MDPI AG
2021-12-01
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| Col·lecció: | Journal of Developmental Biology |
| Matèries: | |
| Accés en línia: | https://www.mdpi.com/2221-3759/10/1/1 |