Mixed T Helper1/T Helper2/T Cytotoxic Profile in Subjects with Chronic Chagas Disease with Hypersensitivity Reactions to Benznidazole

Mixed T Helper1/T Helper2/T Cytotoxic Profile in Subjects with Chronic Chagas Disease with Hypersensitivity Reactions to Benznidazole

ABSTRACT Dermatitis is the most common adverse event during treatment with benznidazole in chronic Chagas disease and is probably mediated by T cells. A set of molecules representative of the different type IV hypersensitivity reactions was evaluated in the circulation and skin biopsies of Trypanoso...

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Main Authors: Melisa D. Castro Eiro, María A. Natale, María G. Alvarez, Araceli Castro, Débora Seigelshifer, Rodolfo Viotti, Marisa Fernández, Luis Mazzuoccolo, Bruno Lococo, Graciela L. Bertocchi, Gonzalo Cesar, María C. Albareda, María J. Elias, María B. Caputo, Eduardo Gaddi, Jeanette Balbaryski, Carlos A. Vigliano, Susana A. Laucella
Format: Article
Language:English
Published: American Society for Microbiology 2022-08-01
Series:Microbiology Spectrum
Subjects:
benznidazole
adverse drug reaction
Trypanosoma cruzi
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01357-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.01357-22

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