Hydrogen-Rich Saline Alleviates Kidney Fibrosis Following AKI and Retains Klotho Expression

Hydrogen-Rich Saline Alleviates Kidney Fibrosis Following AKI and Retains Klotho Expression

Purpose: Acute kidney injury (AKI) is a prominent risk factor for the development of chronic kidney disease (CKD). To date, the related mechanism and effective therapy have not been rigorously explored. The present study aims to investigate the reno-protection of hydrogen-rich saline (HRS) against i...

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Bibliographic Details
Main Authors: Jing Chen, Han Zhang, Jiachang Hu, Yulu Gu, Ziyan Shen, Linghan Xu, Xueqi Jia, Xiaoyan Zhang, Xiaoqiang Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Pharmacology
Subjects:
Klotho
acute kidney injury
fibrosis
hydrogen
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00499/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00499/full

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