Biology and Genomics of an Historic Therapeutic Escherichia coli Bacteriophage Collection

Biology and Genomics of an Historic Therapeutic Escherichia coli Bacteriophage Collection

We have performed microbiological and genomic characterization of an historic collection of nine bacteriophages, specifically infecting a K1 E. coli O18:K1:H7 ColV+ strain. These phages were isolated from sewage and tested for their efficacy in vivo for the treatment of systemic E. coli infection in...

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Bibliographic Details
Main Authors: Abiyad Baig, Joan Colom, Paul Barrow, Catherine Schouler, Arshnee Moodley, Rob Lavigne, Robert Atterbury, Jens Peter Christensen, Dziuginta Jakociune, Jeroen Wagemans
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Microbiology
Subjects:
Escherichia coli
bacteriophage
therapeutics
one-step growth curve
transmission electron microscopy
phylogeny
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01652/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.01652/full

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