Bioinformatics and computational chemistry approaches to explore the mechanism of the anti-depressive effect of ligustilide

Abstract Depression affects people with multiple adverse outcomes, and the side effects of antidepressants are troubling for depression sufferers. Aromatic drugs have been widely used to relieve symptoms of depression with fewer side effects. Ligustilide (LIG) is the main component of volatile oil i...

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Bibliographic Details
Main Authors: Kun Zhang, Chaoguo Zhang, Xiuli Teng, Ke Wang, Mingwei Chen
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-32495-7