BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss

BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss

Osteoporosis is a common aging-related metabolic disease that mainly occurs in older adults and postmenopausal women. Despite advances in anti-osteoporosis treatment, outcomes remain unsatisfactory due to detrimental side effects. BCI hydrochloride (BCI), a selective dual-specificity phosphatase 6 (...

Full description

Bibliographic Details
Main Authors: Chenhui Cai, Wenhui Hu, Ying Zhang, Xu Hu, Sizhen Yang, Hao Qiu, Rujie Wang, Min Ma, Yiyun Qiu, Tongwei Chu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Pharmacology
Subjects:
osteoclast
bone resorption
postmenopausal osteoporosis
bioinformatics
BCI
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.772540/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.772540/full

Similar Items