MicroRNA dysregulation in ataxia telangiectasia

MicroRNA dysregulation in ataxia telangiectasia

IntroductionAtaxia telangiectasia (AT) is a rare disorder characterized by neurodegeneration, combined immunodeficiency, a predisposition to malignancies, and high clinical variability. Profiling of microRNAs (miRNAs) may offer insights into the underlying mechanisms of complex rare human diseases,...

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Main Authors: Emilia Cirillo, Antonietta Tarallo, Elisabetta Toriello, Annamaria Carissimo, Giuliana Giardino, Antonio De Rosa, Carla Damiano, Annarosa Soresina, Raffaele Badolato, Rosa Maria Dellepiane, Lucia A. Baselli, Maria Carrabba, Giovanna Fabio, Patrizia Bertolini, Davide Montin, Francesca Conti, Roberta Romano, Elisa Pozzi, Giulio Ferrero, Roberta Roncarati, Manuela Ferracin, Alfredo Brusco, Giancarlo Parenti, Claudio Pignata
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-08-01
Series:Frontiers in Immunology
Subjects:
ataxia telangiectasia
microRNA
immunodeficiency
cancer
DNA repair
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1444130/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1444130/full

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