Prolonged Absence of Mechanoluminal Stimulation in Human Intestine Alters the Transcriptome and Intestinal Stem Cell NicheSummary

Background & Aims: For patients with short-bowel syndrome, intestinal adaptation is required to achieve enteral independence. Although adaptation has been studied extensively in animal models, little is known about this process in human intestine. We hypothesized that analysis of matched specime...

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Bibliographic Details
Main Authors: Minna M. Wieck, Christopher R. Schlieve, Matthew E. Thornton, Kathryn L. Fowler, Mubina Isani, Christa N. Grant, Ashley E. Hilton, Xiaogang Hou, Brendan H. Grubbs, Mark R. Frey, Tracy C. Grikscheit
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X17300139