IL-8/CXCR1/2 signalling promotes tumor cell proliferation, invasion and vascular mimicry in glioblastoma

IL-8/CXCR1/2 signalling promotes tumor cell proliferation, invasion and vascular mimicry in glioblastoma

Abstract Background Glioblastoma multiforme (GBM) is one of the lethal malignant tumors of the central nervous system. Despite advances made in understanding this complex disease, little has been achieved in improving clinical efficacy towards it. Factors such as chemokines play important role in sh...

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Bibliographic Details
Main Authors: Ira Sharma, Avninder Singh, Fouzia Siraj, Sunita Saxena
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Journal of Biomedical Science
Subjects:
IL-8
IL-8-CXCR1/2
Glioblastoma
Vascular mimicry
GBM progression
Online Access:http://link.springer.com/article/10.1186/s12929-018-0464-y

Internet

http://link.springer.com/article/10.1186/s12929-018-0464-y

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