Astrocyte remodeling without gliosis precedes optic nerve axonopathy

Astrocyte remodeling without gliosis precedes optic nerve axonopathy

Abstract Astroyctes serve myriad functions but are especially critical in white matter tracts, where energy-demanding axons propagate action potentials great distances between neurons. Axonal dependence on astrocytes for even normal function accentuates the critical role astrocytes serve during dise...

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Bibliographic Details
Main Authors: Melissa L. Cooper, John W. Collyer, David J. Calkins
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Acta Neuropathologica Communications
Subjects:
Neurodegeneration
Glaucoma
Glia
Astrocytes
Retinal ganglion cell
Connexin 43
Online Access:http://link.springer.com/article/10.1186/s40478-018-0542-0

Internet

http://link.springer.com/article/10.1186/s40478-018-0542-0

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