Mannosylated-Chitosan-Coated Andrographolide Nanoliposomes for the Treatment of Hepatitis: In Vitro and In Vivo Evaluations

Mannosylated-Chitosan-Coated Andrographolide Nanoliposomes for the Treatment of Hepatitis: In Vitro and In Vivo Evaluations

A key diterpene lactone of Andrographis paniculata, i.e., andrographolide (AG), exhibits a variety of physiological properties, including hepatoprotection. The limited solubility, short half-life, and poor bioavailability limits the pharmacotherapeutic potential of AG. Therefore, in this study we ai...

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Bibliographic Details
Main Authors: Sayali Pravin Metkar, Gasper Fernandes, Ajinkya Nitin Nikam, Soji Soman, Sumit Birangal, Raviraja N Seetharam, Manjunath Bandu Joshi, Srinivas Mutalik
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Membranes
Subjects:
andrographolide
liposomes
mannosylated chitosan
bioavailability enhancement
Online Access:https://www.mdpi.com/2077-0375/13/2/193

Internet

https://www.mdpi.com/2077-0375/13/2/193

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