Immunotherapy and radiotherapy for older patients with locally advanced rectal cancer unfit for surgery or decline surgery: a practical proposal by the International Geriatric Radiotherapy Group

Immunotherapy and radiotherapy for older patients with locally advanced rectal cancer unfit for surgery or decline surgery: a practical proposal by the International Geriatric Radiotherapy Group

The standard of care for locally advanced rectal cancer is total neoadjuvant therapy followed by surgical resection. Current evidence suggests that selected patients may be able to delay or avoid surgery without affecting survival rates if they achieve a complete clinical response (CCR). However, fo...

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Bibliographic Details
Main Authors: Nam P. Nguyen, Mohammad Mohammadianpanah, Arthur SunMyint, Brandi R. Page, Vincent Vinh-Hung, Olena Gorobets, Meritxell Arenas, Thandeka Mazibuko, Huan Giap, Maria Vasileiou, Fabien Dutheil, Carmelo Tuscano, ULF Lennart Karlsson, Zineb Dahbi, Elena Natoli, Eric Li, Lyndon Kim, Joan Oboite, Eromosele Oboite, Satya Bose, Te Vuong
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Oncology
Subjects:
older
rectal cancer
locally advanced
CPI
radiotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1325610/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2024.1325610/full

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