PTEN deficiency potentiates HBV-associated liver cancer development through augmented GP73/GOLM1

PTEN deficiency potentiates HBV-associated liver cancer development through augmented GP73/GOLM1

Abstract Background Although hepatitis B virus (HBV) infection is a major risk factor for hepatic cancer, the majority of HBV carriers do not develop this lethal disease. Additional molecular alterations are thus implicated in the process of liver tumorigenesis. Since phosphatase and tensin homolog...

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Bibliographic Details
Main Authors: Fuqiang Huang, Jing Guo, Na Zhao, Mengjie Hou, Xiaochen Gai, Shuhui Yang, Pei Cai, Yanan Wang, Qian Ma, Qi Zhao, Li Li, Huayu Yang, Yanling Jing, Di Jin, Zhongdong Hu, Xiaojun Zha, Hongyang Wang, Yilei Mao, Fangming Liu, Hongbing Zhang
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Journal of Translational Medicine
Subjects:
Hepatocellular carcinoma
Intrahepatic cholangiocarcinoma
Hepatitis B virus
Pten
GP73
Online Access:https://doi.org/10.1186/s12967-024-04976-4

Internet

https://doi.org/10.1186/s12967-024-04976-4

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