The m6A reader YTHDF3-mediated PRDX3 translation alleviates liver fibrosis

Peroxiredoxin 3 (PRDX3) acts as a master regulator of mitochondrial oxidative stress and exerts hepatoprotective effects, but the role of PRDX3 in liver fibrosis is not well understood. N6-methyladenosine (m6A) is considered the most prevalent posttranscriptional modification of mRNA. This study aim...

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Bibliographic Details
Main Authors: Ruimin Sun, Xinyao Tian, Yang Li, Yan Zhao, Zhecheng Wang, Yan Hu, Lijun Zhang, Yue Wang, Dongyan Gao, Shusen Zheng, Jihong Yao
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722001501