Human genetic adaptation related to cellular zinc homeostasis.

SLC30A9 encodes a ubiquitously zinc transporter (ZnT9) and has been consistently suggested as a candidate for positive selection in humans. However, no direct adaptive molecular phenotype has been demonstrated. Our results provide evidence for directional selection operating in two major complementa...

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Bibliographic Details
Main Authors: Ana Roca-Umbert, Jorge Garcia-Calleja, Marina Vogel-González, Alejandro Fierro-Villegas, Gerard Ill-Raga, Víctor Herrera-Fernández, Anja Bosnjak, Gerard Muntané, Esteban Gutiérrez, Felix Campelo, Rubén Vicente, Elena Bosch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-09-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010950&type=printable