Natural killer or natural killer/T cell lineage large granular lymphocytosis associated with dasatinib therapy for Philadelphia chromosome positive leukemia

Dasatinib, a dual tyrosine kinase inhibitor, is known to modulate or suppress T-cell activation and proliferation. We report a series of 8 patients who developed chronic peripheral lymphocytosis, identified as natural killer cells or natural killer/T-cells based on their large granular lymphocyte mo...

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Bibliographic Details
Main Authors: Dong Hwan Kim, Suzanne Kamel-Reid, Hong Chang, Robert Sutherland, Chul Won Jung, Hyeoung-Joon Kim, Je-Jung Lee, Jeffrey H. Lipton
Format: Article
Language:English
Published: Ferrata Storti Foundation 2009-01-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/5129