Clinical efficacy of Yukgunja-tang combined with a proton pump inhibitor for refractory gastroesophageal reflux disease: study protocol for randomized, double-blind, double-dummy clinical trial

Clinical efficacy of Yukgunja-tang combined with a proton pump inhibitor for refractory gastroesophageal reflux disease: study protocol for randomized, double-blind, double-dummy clinical trial

Abstract Background Yukgunja-tang (YGJ) is an herbal prescription used to treat the symptoms of gastroesophageal reflux disease (GERD). Although many preclinical and clinical studies on YGJ have been conducted on GERD, there is a lack of evidence from blinded studies to exclude placebo effects. Ther...

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Bibliographic Details
Main Authors: Na-Yeon Ha, Jung-Wook Kim, Jinsung Kim
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Gastroesophageal reflux disease
Herbal medicine
Botanical drug
Yukgunja-tang
Liujunzi-tang
Rikkunshito
Online Access:https://doi.org/10.1186/s12906-023-04283-3

Internet

https://doi.org/10.1186/s12906-023-04283-3

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